Acetyl-CoA Carboxylase alpha anticorps (AA 2223-2346)

N° du produit ABIN5701229

L’anticorps Lapin Polyclonal anti-Acetyl-CoA Carboxylase alpha a été validé pour WB, IHC, ELISA, IP et IF. Il convient pour détecter Acetyl-CoA Carboxylase alpha dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Acetyl-CoA Carboxylase alpha anticorps (AA 2223-2346) (ABIN5701229)

Antigène: Acetyl-CoA Carboxylase alpha (ACACA)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Acetyl-CoA Carboxylase alpha est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Détail du produit anti-Acetyl-CoA Carboxylase alpha anticorps

Épitope: AA 2223-2346

Fonction: ACACA antibody

Immunogène:

Immunogen sequence: 2223-2346aa

Immunogen: acetyl-Coenzyme A carboxylase alpha

Isotype: IgG

Information d'application

Indications d'application: WB :1:200-1:2000,IHC:1:20-1:200,IF:1:20-1:200,IP:1:200-1:2000

Commentaires:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab00077(ACACA antibody) at dilution of 1:500

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur Acetyl-CoA Carboxylase alpha

Antigène: Acetyl-CoA Carboxylase alpha (ACACA)

Autre désignation: ACACA

Sujet:

Synonyms: Acetyl-CoA carboxylase 1 (ACC1)|Acetyl-Coenzyme A carboxylase alpha (ACC-alpha)|ACACA|ACAC|ACC1|ACCA

Background: ACACA(Acetyl-CoA carboxylase 1, ACC), also named as ACAC, ACC1 and ACCA, belongs to the biotin containing enzyme family. It catalyzes the synthesis of malonyl-CoA, which is an intermediate substrate playing a pivotal role in the regulation of fatty acid metabolism and energy production. ACACA is involved in the biosynthesis of fatty acids, and malonyl-CoA produced is used as a building block to extend the chain length of fatty acids by fatty acid synthase(FAS)(PMID:19900410). It has 4 isoforms produced by alternative promoter usage with the molecular weight between 260 kDa and 270 kDa.

Poids moléculaire: 270kDa

UniProt: Q13085

Pathways: AMPK Signaling, Ribonucleoside Biosynthetic Process, L'effet Warburg